IMPORTANT SAFETY INFORMATION: STIVARGA can cause liver problems, which can be serious and sometimes lead to death. Your healthcare provider will do blood tests... Continue reading below
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Additional support

Everyone living with a cancer diagnosis could use some support along the way. Here you will find information and tools you need to stay informed and connected, including:

  • 3 videos designed to help people who are just starting STIVARGA® (regorafenib)
  • Patient Starter Kits for those new to treatment with STIVARGA
  • Disease-specific information and support

These resources can help you learn more about your cancer, where to seek financial help, and how to connect with other patient support and advocacy groups.

Maria’s story
Helpful videos
STIVARGA starter kit
More support resources

Support may be closer than you think!

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Important Tips and Reminders

Download the STIVARGA Tip Sheet for information on taking and storing STIVARGA, low-fat meal options, and educational and financial support.

Contact these resources if you have CRC and need additional support:

Colon Cancer Alliance

Fight Colorectal Cancer

American Cancer Society (ACS)

Association of Cancer
Online Resources (ACOR)


Contact these resources if you have GIST and need additional support:

The Life Raft Group

GIST Support International

Liddy Shriver
Sarcoma Initiative

Cancer Hope Network

Family Caregiver Alliance


STIVARGA (regorafenib) is a prescription medicine used to treat people with:

It is not known if STIVARGA is safe and effective in children less than 18 years of age.

Important Safety Information

STIVARGA (regorafenib) can cause liver problems, which can be serious and sometimes lead to death. Your healthcare provider will do blood tests to check your liver function before you start taking STIVARGA and during your treatment with STIVARGA to check for liver problems. Tell your healthcare provider right away if you experience yellowing of your skin or the white part of your eyes, nausea, vomiting, dark urine, or change in your sleep pattern.

Before taking STIVARGA, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the prescription and over-the-counter medicines, vitamins, and herbal supplements you take. Avoid drinking grapefruit juice and taking St. John’s Wort while taking STIVARGA.

STIVARGA may cause serious side effects, including:

The most common side effects with STIVARGA include pain including stomach-area (abdomen); tiredness, weakness, fatigue; diarrhea (frequent or loose bowel movements); decreased appetite; infection; voice change or hoarseness; increase in certain liver function tests; fever; swelling, pain, and redness of the lining in your mouth, throat, stomach, and bowel (mucositis); and weight loss.

For important risk and use information about STIVARGA, please see the full Prescribing Information, including Boxed Warning.

You are encouraged to report negative side effects or quality complaints of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.