IMPORTANT SAFETY INFORMATION: STIVARGA can cause liver problems, which can be serious and sometimes lead to death. Your healthcare provider will do blood tests... Continue reading below
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3 Ways to Get STIVARGA

Because STIVARGA is a specialized anticancer medicine, it is not available at retail pharmacies. You can get your medicine in 3 easy ways:

Specialty pharmacy
provider (SPP)

When filing a prescription through an SPP, you will likely receive your medicine through the mail.

SPP employees:
  • Work directly with your oncology team and health insurance providers to coordinate your care
  • Will assist with delivery/payment details and support programs

The Resources for Expert Assistance and Care Helpline (REACH) provides nursing support, financial assistance, and help with taking STIVARGA.

Contact a REACH counselor at 1-866-639-2827.

Doctor's office

You may receive your medicine at a doctor's office if an on-site pharmacy is available.

Support services after receiving STIVARGA
  • Patient education materials, including a starter kit
  • Side effect management follow-ups and refill reminders
  • Counseling for patients newly taking STIVARGA


STIVARGA (regorafenib) is a prescription medicine used to treat people with:

It is not known if STIVARGA is safe and effective in children less than 18 years of age.

Important Safety Information

STIVARGA (regorafenib) can cause liver problems, which can be serious and sometimes lead to death. Your healthcare provider will do blood tests to check your liver function before you start taking STIVARGA and during your treatment with STIVARGA to check for liver problems. Tell your healthcare provider right away if you experience yellowing of your skin or the white part of your eyes, nausea, vomiting, dark urine, or change in your sleep pattern.

Before taking STIVARGA, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the prescription and over-the-counter medicines, vitamins, and herbal supplements you take. Avoid drinking grapefruit juice and taking St. John’s Wort while taking STIVARGA.

STIVARGA may cause serious side effects, including:

The most common side effects with STIVARGA include pain including stomach-area (abdomen); tiredness, weakness, fatigue; diarrhea (frequent or loose bowel movements); decreased appetite; infection; voice change or hoarseness; increase in certain liver function tests; fever; swelling, pain, and redness of the lining in your mouth, throat, stomach, and bowel (mucositis); and weight loss.

For important risk and use information about STIVARGA, please see the full Prescribing Information, including Boxed Warning.

You are encouraged to report negative side effects or quality complaints of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.