IMPORTANT SAFETY INFORMATION: STIVARGA can cause liver problems, which can be serious and sometimes lead to death. Your healthcare provider will do blood tests... Continue reading below
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Helping you get and pay for your medicine

Because STIVARGA® (regorafenib) is a specialized anticancer medicine, it is not available at retail pharmacies. You can get your medicine in 3 easy ways:

3 Ways to Get STIVARGA
By accessing REACH® (Resources for Expert Assistance and Care Helpline). The REACH program provides you with nursing support and trusted guidance on taking STIVARGA, as well as financial assistance services
Call 1-866-639-2827 to contact a REACH counselor today
Through a network of specialty pharmacy providers (SPPs). SPPs help new patients start on therapy, provide access to counselors, and ensure fast, reliable delivery of prescriptions
Doctor's Office
At your doctor’s office, if an on-site pharmacy is available
REACH patient program
Access to STIVARGA
$0 Co-Pay program*

Specialty medicine needs specialty support

Your insurance company may require you to fill your prescription for STIVARGA through a specialty pharmacy provider (SPP). Employees of an SPP can work directly with the members of your oncology team, and sometimes your health insurance provider, to coordinate your care.

Your doctor may also fill your prescription at the office, if an on-site pharmacy is available.

Getting started with an SPP

As with any medicine for cancer, your oncologist will write you a prescription for STIVARGA. However, when you fill a prescription through an SPP, it's likely you will receive your medicine through the mail.

  • A member of the SPP may reach out to you to confirm any co-payment information or shipping information
  • They may also want to discuss any support programs the SPP offers

Getting started with your medicine

Once you are on board with an SPP or on-site pharmacy, your prescription will arrive quickly. In many cases, your first prescription will come with a starter kit and other patient education materials.

However, support does not end there! STIVARGA offers you these additional services throughout your treatment:

  • Follow-up on various topics, including side effect management information and refill reminders
  • Confirmed delivery of STIVARGA and patient support materials
  • Counseling for patients who are just starting on therapy with STIVARGA

Providing support

You can call the SPP directly for information, but remember, their assistance is not a substitute for your doctor/healthcare provider.


STIVARGA (regorafenib) is a prescription medicine used to treat people with:

It is not known if STIVARGA is safe and effective in children less than 18 years of age.

Important Safety Information

STIVARGA (regorafenib) can cause liver problems, which can be serious and sometimes lead to death. Your healthcare provider will do blood tests to check your liver function before you start taking STIVARGA and during your treatment with STIVARGA to check for liver problems. Tell your healthcare provider right away if you experience yellowing of your skin or the white part of your eyes, nausea, vomiting, dark urine, or change in your sleep pattern.

Before taking STIVARGA, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the prescription and over-the-counter medicines, vitamins, and herbal supplements you take. Avoid drinking grapefruit juice and taking St. John’s Wort while taking STIVARGA.

STIVARGA may cause serious side effects, including:

The most common side effects with STIVARGA include pain including stomach-area (abdomen); tiredness, weakness, fatigue; diarrhea (frequent or loose bowel movements); decreased appetite; infection; voice change or hoarseness; increase in certain liver function tests; fever; swelling, pain, and redness of the lining in your mouth, throat, stomach, and bowel (mucositis); and weight loss.

For important risk and use information about STIVARGA, please see the full Prescribing Information, including Boxed Warning.

You are encouraged to report negative side effects or quality complaints of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.