IMPORTANT SAFETY INFORMATION: STIVARGA can cause liver problems, which can be serious and sometimes lead to death. Your healthcare provider will do blood tests... Continue reading below
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Additional support

Everyone living with a cancer diagnosis could use some support along the way. Here you will find information and tools you need to stay informed and connected, including:

  • Patient Starter Kits for those new to treatment with STIVARGA® (regorafenib)
  • Disease-specific information and support

These resources can help you learn more about your cancer, where to seek financial help, and how to connect with other patient support and advocacy groups.

STIVARGA starter kit
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More support resources
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Your STIVARGA patient starter kit components

When you start treatment with STIVARGA, you will receive a complimentary Patient Starter Kit with the following materials:

STIVARGA	(regorafenib) Patient Brochure thumbnail
Patient Brochure

Provides an overview of what STIVARGA is, how it can help, and what to expect during treatment

STIVARGA (regorafenib) Treatment Journal thumbnail
Treatment Journal

Helps you keep track of your STIVARGA tablets and record your general health

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Comfort Tools

Lotion and socks for hand-foot-skin reactions and a coupon for additional lotion


STIVARGA® (regorafenib) is a prescription medicine used to treat people with:

It is not known if STIVARGA is safe and effective in children less than 18 years of age

Important Safety Information

STIVARGA can cause liver problems which can be serious and sometimes lead to death. Your healthcare provider will do blood tests to check your liver function before you start taking STIVARGA and during your treatment with STIVARGA to check for liver problems. Tell your healthcare provider right away if you experience yellowing of your skin or the white part of your eyes, nausea, vomiting, dark urine, or changes in your sleep pattern.

Before taking STIVARGA, tell your healthcare provider about all of your medical conditions, including if you:

Tell your healthcare provider about all the prescription and over-the-counter medicines, vitamins, and herbal supplements you take. Avoid drinking grapefruit juice and taking St. John's Wort during treatment with STIVARGA.

STIVARGA may cause serious side effects, including:

The most common side effects with STIVARGA include tiredness, weakness, fatigue; diarrhea (frequent or loose bowel movements); loss of appetite; swelling, pain, and redness of the lining in your mouth, throat, stomach, and bowel (mucositis); voice changes or hoarseness; infection; pain in other parts of your body; weight loss; abdomen (stomach-area) pain; fever; and nausea.

These are not all of the possible side effects of STIVARGA. For more information, ask your healthcare provider or pharmacist.

Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment with STIVARGA if you have certain side effects.

Tell your doctor if you have any side effects that bother you or that do not go away.

For important risk and use information about STIVARGA, please see the full Prescribing Information, including Boxed Warning.

You are encouraged to report negative side effects or quality complaints of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.